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In vivo , atrial effective refractory period (ERP) was reduced by GLP-1 (see Supplementary material online, Figure S5B ), which was confirmed in the isolated perfused pig heart, and found to be dependent on the GLP-1 receptor (see Supplementary material online, Figure S5C )
In an embryofetal development study in pregnant rabbits, subcutaneous doses of 0.0010, 0.0025 or 0.0075 mg/kg/day (0.06-, 0.6- and 4.4-fold the MRHD) were administered throughout organogenesis from Gestation Day 6 to 19
In addition, its encouraged to continue to work with healthcare providers, such as nutritionists or weight loss coaches